Occupational hazard is something unpleasant conditions, circumstances, or combinations of factors that you may suffer or experience as a result of doing your job or hobby. It is many types like biological, infectious, physical, psychological, and allergic. The radicular cyst arises from epithelial remnants stimulated to proliferated by an inflammatory process originating from pulpal necrosis of a non vital tooth. This article infected radicular cyst associated with maxillary lateral incisor (12) due to the occupational hazard in a 21 year male patient treated with the help of endodontic procedure, extraction of offending tooth, enucleation with primary closure.