Diabetes has a significant incidence of illness, health care effects and lead to a high mortality rate due to its complications in both developed and developing countries so far. Diabetes can be divided into three main types: Type 1 diabetes, Type 2 diabetes and Gestational diabetes, the most common type is Type 2 diabetes (T2D). Our work focuses on researching the relationship of complications and their cost of treatment in order to make the treatment plan and minimize its costs in at the Thanh Nhan hospital in Hanoi, Vietnam. Therefore, the research results show that there are many different types and rates of complications of T2D depending on key factors such as: age and duration of the disease, by determining the complication rate and analyzing multivariate logistic regression models to find the risk factors associated with an increase in the number of complications of the disease from the Social Science Package Statistics (SPSS) software and other.