Background: This study was undertaken to estimate the incidence, etiological factor, time of onset & clinical types of neonatal seizures in our setup and to study the biochemical abnormalities among the different types of neonatal seizures in our setup. Methods: This is a hospital based prospective observational study conducted in neonatal ICU, department of paediatrics, BMCRI during period of January 2020 to March 2022. Results: Total number of patients which developed neonatal seizures were 82 in our study. The proportion of neonatal seizures among NICU admission of inborn patients were 10.8%. Out of 82 babies of neonatal seizures, 45 (54.8%) were males and 37(45.12%) were females in the ratio of 1.2:1, with male preponderance. Out of 82 babies who developed neonatal seizures, it was found that 50(60.9%) were pre-term babies, 28(34.14%) were term babies and 4(4.87%) were post-term babies. In this study out of 82 babies, 45 neonates (54.8%) were LBW babies and 37 (45.12%) were of >=2.5kg birthweight. Out of 82 neonates, in 35 (42.6%) neonates seizure occurred between 24-72hrs whereas in 28 (34.14%) neonates seizure occurred in <24hrs and in 19 (23.17%) babies seizure occurred in >72hrs which shows that most of seizures were observed between 24-72hrs of life. In this study, out of 82 cases, neonates with subtle seizures were 40(48.78%), neonates with tonic seizures were 32(39.02%), neonates with focal clonic were 8(9.75%) and the multifocal clonic seizures were 2(2.43%)