Aim and objectives: Hypertension and increased heart rate are prevalent during laryngoscopy and tracheal intubation. Acute LV failure, dysrhythmias, IC haemorrhage, pulmonary edoema and myocardial infarction are all possible complications. Patients with hypertension had a heightened pressor response, despite being preoperatively normalized with anti-hypertensive medication. The purpose of this research is to see if melatonin is more effective than a placebo at reducing the Haemodynamic reactions to laryngoscopy and endotracheal intubation. Research into the effects of melatonin on extubation response and intraoperative hemostasis is also a goal.