Abstract: The presence of numerous keratin pearls on microscopic study is a feature commonly seen in well-differentiated squamous cell carcinoma. Pleomorphic adenoma (PA) can show the presence of squamous metaplasia with keratin pearls as a rare finding. This article present a short review on this rare variant of pleomorphic adenoma which exuberant squamous metaplasia and keratin cysts formations in salivary gland keratinizing pleomorphic adenoma .