Cardiovascular disease is still the leading cause of death. In our tertiary care centre, we looked at the change in outcomes for anterior ST-elevation myocardial infarction (STEMI) between January 2017 and December 2021. Over the last five years, 1,658 patients with anterior STEMI who presented to our centre underwent primary percutaneous coronary intervention within 12 hours of their arrival. We gathered demographic, clinical, and mortality data during a five-year period and divided it into four quartiles: 2017-2018 (n=312), 2019 (n=408), 2020 (n=428), and 2021 (n=510).