Background: With the implementation of the new competency based curriculum in the Indian medical education system in 2019 there has been adoption of innovative tools to make teaching and learning student-centric. The education system is changing from teaching facts to empowering students to learn how to look for relevant information and organise it for better learning. Flipped classroom is one such model where the learner is assigned didactic lecture material before the class and the class room is used for face to face interaction to inculcate a higher level of thinking amongst the students. At this juncture this study has been conducted to see the effectiveness and feasibility of implementing flipped classroom in teaching biochemistry to Phase I MBBS students.