Resume. The article presents information about the hygienic state of the oral cavity, the state of periodontal tissues, the level of hygienic knowledge and measures of therapeutic and prophylactic measures among workers of silk-winding production. The object of study was 97 workers of the alkaline-winding industry "Bukhara Brilliant Silk", who are exposed to industrial noise, as one of the harmful production factors, also the dustiness of the air in working rooms in various workshops and, in terms of importance, harmful, production factors are microclimatic conditions, at the age of 29 59 years. The control group consisted of 44 employees of the administrative and managerial apparatus, whose work process excludes the impact of factors of the working environment. The results of the research revealed the total prevalence of diseases of hard tissues of teeth (99.1%) and periodontal disease (100%) among workers of the alkaline industry "Bukhara Brilliant Silk", a high prevalence of diseases of the oral mucosa - 58.7%, a low level of oral hygiene and hygiene knowledge. There is an obvious need to develop a targeted prevention program, including a comprehensive - individual, professional oral hygiene and health education.