Abstract : Soil salinity affects several physiological and biochemical processes in plants. Plant culture of mixed composition and different concentrations of salt treatments were applied for 10 days to detect the response of the salinity tolerant variety of Rice regarding growth, survival, plant height, leaf area, leaf injury, relative growth rate. In vitro superoxide dismutase (SOD), ascorbate peroxidase (APX) and catalase (CAT) activities in the leaves are also screened. Most influenced genotype was IR-64 in terms of growth and dry matter and PB-1 for root length. Maximum SOD activity was recorded in PB-1 followed by IR-64. However, HKR-127 the minimum SOD activity was recorded. APX activity showed large variation in rice genotypes following Sodium chloride (NaCl) treatment. APX activity increased significantly in PB-1 over control in dose dependent manner in all the treated samples. The maximum (25.0%) APX activity was observed in PB-1 at T4 treatment over control. Salt treatment remarkably increased the APX activity in IR-64 up to T3 level of NaCl treatment. In HKR-127 genotype at all levels of treatments there was non-significant increase in its activity. Moreover, Catalase activity in PB-1 increased significantly with all the treatments. The difference among treatments was significant at all levels the highest activity (26.3%) was at T4 level of treatment in PB-1 genotype. IR-64 genotype showed increased catalase activity up to T3 level while in HKR127 increased non-significantly in CAT at all treatments. The data are discussed in regard to implications of salt stress.