Background: Cervical cancer is among the most frequent cancer types in women worldwide. Radiotherapy, including external beam radiation and brachytherapy, is one of the commonly used treatment options for cervical cancer. However, the response and adverse effects of radiation therapy on cervical cancer survival have been poorly investigated with inconclusive result. Therefore, the aim of this study was possibly to explore the potential factors that might affect the response to radiotherapy in patients affected with cervical cancer and thus providing information for an eminent decision making in a way to a better therapy.