The biofunctional prosthetic system (BPS) is designed in such a way that there is better comfort, function and aesthetic to the patient. The impression making and recording the maxillomandibular relation is a standardised in BPS method, this makes the dentist to understand the subject and makes things easier. There are 4 clinical procedures in BPS technique, which reduces the appointment time for the patient. With all the shortcomings of conventional complete denture and advantages of biofunctional prosthesis, we conducted a retrospective analysis of aesthetic outcome of complete denture constructed with biofunctional prosthetic system conducted in private university setup. A retrospective study was done in which 45 BPS dentures were placed from 1 June 2019 till 1 March 2020 were included. Data was reviewed from the patients records and analysed the data of 86,000 patients between June 2019 and March 2020 that were documented in a private institute. Data were analyzed with descriptive statistics. Chi Square test and Pearson’s correlation was done for assessing the correlation between age and all the parameters checked, and between gender and all the parameters. Out of 45 patients, 44.4% BPS dentures were fabricated for the age group of 61-70 years. 51.1% of the patients were Males. Out of the total population for 55.6% of the population square shaped teeth were used and for 44.4% of the population tapered teeth were used. 53.3% of the population had premolar to premolar smile, while 31.1% of the population had molar to molar and 15.6% had canine to canine smile. In 82.2% of the teeth setting, the intercanine width matched the interalar width. 37.8% of the population had complete exposure of anterior teeth on smiling. According to our reviewers 62.2% of patients' smiles were attractive. From the present study, it can be concluded that the shape of the teeth showed a significant difference in perception among the individuals whereas the other parameters showed no difference.