Introduction: Failure in achieving the coronal marginal integrity could possibly questions the prognosis of the endodontically treated teeth. The success and the aim of an endodontic therapy tends to reduce infection in the root canal system and to eliminate reinfection from the apical and coronal region. Materials and Methodology: A total of 80 freshly extracted, intact human mandibular premolars were selected and being used for this study. 40 samples were irrigated with 2 mL of 3% sodium hypochlorite and 17% EDTA, finally rinsed with saline. For another 40 samples irrigation regimen was 2 ml of 3% sodium hypochlorite and tublicid plus, finally rinsed with saline. Coronal section of 4 mm length was used in this study which was further obtained by sectioning tooth horizontally with diamond disk. All the samples were prepared so that they have a through and through channel and were coated superficially with three layers of nail varnish and were then autoclaved. Each group comprising of 40 samples were again sub grouped into two such that each has 20 teeth (n=20) and restored with nanocomposite and nano glass ionomer cement based on the manufacturer protocols.