Purpose: Assessing the reality of nursing knowledge and practice about falls prevention for patients at Nam Dinh General Hospital. Method: Descriptive study cross-section with the participation of 170 nurses directly taking care of people in clinical departments of Nam Dinh General Hospital from December 2019 to June 2020. Results: The percentage of nurses with general knowledge is 56.5%. Of these, 51.8% of nurses said that there was no risk of falling for the patient in the hospital, 91.2% of the nurses said that the hospital should not develop a fall risk assessment form and only 3, 5% of nurses said that the patient's risk of falling due to physiological problems could be prevented by providing a safe environment; for example: clear road to the bathroom, no clutter room, good shoes. The proportion of nurses who self-assessed practice for general fall prevention for patients was 48.8%. Conclusion: The level of nursing knowledge and practice of falls prevention is not high in the nursing home. There is a relationship between knowledge and practice of falling prevention in the patient. The research results show the need to strengthen nursing knowledge about fall prevention in patients.