ABSTRACT Sella turcica is a saddle shaped bony structure present on the sphenoid bone. The pituitary gland is seated at the inferior aspect of the sella turcica, called hypophyseal fossa. Sella turcica serves as a cephalometric landmark, that being said any morphological changes can affect the overall craniometry of the individual as well as alter the function of the structures it lodges. The following review emphasis on the possible morphological changes of sella turcica and its effects on the individual.