Aims: To study the effect of yoga asan and pranayam in type 2 diabetes mellitus patient in jhalawar district, rajasthan. Objectives: To determine the effect of manduk asan and kapalbhati in type 2 Diabetes mellitus patients and compare the effect of this asan and pranayam to the control group, who are not practicing any type of asan and pranayam. Material and Methods: This prospective study was conducted by the Department of Physiology, Jhalawar Medical College & Hospital, Jhalawar (Rajasthan) and Yoga OPD in collaboration with the Department of Medicine, the Department of Pathology and the Department of Biochemistry. There were 50 subjects in the study group and 50 in the control group. The goal of this research was to assess the effect of 3-month practice of yoga in subjects with type 2 diabetes mellitus. Results: In the present study, the difference in mean age, sex, height, blood pressure between cases and controls was not important (p > 0.05). Whereas mean fasting glucose levels, HbA1c, BMI were found to be significantly lower in the study group taking the medicine (Oral Hypoglycaemic Drug) with pranayam and yoga compared to control taking the medicine (Oral Hypoglycaemic Drug) without practicing pranayam and yoga (p < 0.05). Conclusion: Yoga is a beneficial supplement to the treatment of a number of conditions that are effective in behavioural lifestyle disorders, including diabetes mellitus. Yoga therapy also improves the status of diabetics in terms of lowering insulin doses, physical and mental alertness, and preventing complications.