Perforation is one of the most dynamic complications of peptic ulcer, in spite of modern management, it is still a life threatening catastrophe. The sudden release of duodenal and gastric contents into the peritoneal cavity through a perforation leads to a devastating sequence of events which if not properly managed, is likely to cause death. Non-traumatic upper gastro intestinal perforation carries a high mortality and morbidity unless early treatment is instituted inform of surgery. This study has been based on the analysis of 50 cases of non-traumatic upper gastro-intestinal perforation (peptic ulcer) admitted to hospital. The cases were collected at random which were admitted and treated in various surgical units. These cases were admitted as emergencies. After admission a detailed history was taken and clinical evaluation was done and possible immediate investigations were done. Guarding & rigidity was present in all 50 cases to a variable extent. In 49 cases obliteration of liver dullness was present. In one case obliteration of liver dullness and gas under diaphragm could not be elicited, because the patient came early to the hospital and his stomach was full at the time of perforation