Ceramics are broadly utilized as circuitous helpful materials in dentistry because of their extensive biocompatibility and satisfying aesthetics. The objective is to review the different CAD/CAM all-ceramic biomaterials. CAD/CAM all-ceramic biomaterials are highlighted and a subsequent literature search was conducted for the relevant subjects utilizing PubMed followed by manual search. Advancements in CAD/CAM innovation have catalyzed inquiry in all-ceramic biomaterials and their applications. Feldspathic glass ceramic and glass penetrated ceramic can be manufactured by conventional research facility strategies or CAD/CAM. The appearance of polycrystalline ceramics may be a coordinate result of CAD/CAM innovation without which the manufacture would not have been conceivable. The clinical employments of these ceramics have met with variable clinical victory. Numerous choices are presently accessible to the clinicians for the creation of aesthetic all ceramic restorations.