Abstract - Relevance: The high prevalence, high risk of social maladjustment as a result of the consequences of acute cerebrovascular accident and, accordingly, one of the main causes of mortality gives cerebrovascular pathology a special status, as evidenced by numerous publications. the task was to identify in the studied patients the entire spectrum of clinical manifestations corresponding to the lesions of the brain structures supplied by the blood vessels of VBD and to determine the presence of a statistically significant dependence of clinical manifestations of COPD. As well as the identification of risk factors and their influence on the rehabilitation of patients with stroke in the vertebrobasilar system. Patients with IS in VBD and COPD - 62 people (group I) - 29 men and 33 women aged 50 to 74 years (59.8 ± 5.8). Patients with IS in VBD - 64 people (group II). Of these, 31 were men and 33 were women aged 51 to 80 years (62.4 ± 5.4). All patients received traditional treatment in the most acute and acute periods of IS, patients with COPD received COPD treatment in parallel with traditional IS therapy. in group I, BMI averaged 29.3 ± 5.8 kg / m2, in men - 28.9 ± 6.3 kg / m2, in women - 29.9 ± 5.1 kg / m2 (the difference is not significant, p = 0.58), while 11 patients (17.7%) had a normal BMI, 1 patient (1.6%) had a body weight deficit, 26 patients (41.9%) had preobesity, 15 patients (24, 2%) had first degree obesity, 9 patients (14.5%) had second degree obesity. Accordingly, preobesity or obesity was recorded in 50 patients of group I (80.65%) (Figure 3.3) And in group II, BMI averaged 28.7 ± 6.1 kg / m2, in men - 27.8 ± 5.7 kg / m2, in women - 30.1 ± 5.6 kg / m2 (the difference is not significant, p = 0.6), while 17 patients (26.6%) had a normal BMI, 3 patients (4.7%) were found to be underweight, 29 patients (45.3%) had preobesity, 8 patients (12 , 5%) had first degree obesity, 7 patients (10.9%) had second degree obesity. Accordingly, preobesity or obesity was recorded in 44 patients of group II (68.8%). In patients of group I, among the clinical manifestations of IS in PBS, ataxia prevailed, which occurred in 35 patients (56.5%), including hemiataxia, which occurred in 20 patients (31.3%). Paresis and paralysis of the limbs were detected in 31 patients (50%). Complaints about a subjective feeling of unsteadiness, instability in an upright position, and imbalance occurred in 25 patients (40.3%). Dysarthria also occurred in 25 cases (40.3%). Nystagmus was detected in 22 cases (35.5%), rotational dizziness (vertigo) - in 20 cases (32.3%), depression of consciousness - in 21 cases (33.9%). Symptoms such as hemianopsia and ophthalmoparesis occurred each in 14 cases (22.6%). Sensory disorders were detected in 12 patients (19.4%), autonomic disorders - in 8 patients (12.9%), diplopia - in 8 patients (12.9%), dysphagia - in 7 patients (11.3%) , aphasia and headache - 6 patients each (9.7% each), dysphonia - 7 patients (11.3%), confusion and visual agnosia - 4 patients each (6.5% each), respiratory failure - 3 patients (4.8%). There were also 2 cases (3.2% each) of amnesia, ignorance syndrome and a feeling of generalized weakness.