Introduction: Cerebral venous thrombosis is mostly an uncommon but severe thrombotic manifestation which has a high mortality rate, has the potential to end in disability and the greater tendency of recurrence. There are some coagulation abnormalities such as gain-of-function mutations in the genes that encodes factor V (factor V Leiden) and prothrombin3 are presented with an increased risk of cerebral vein thrombosis4-6 whereas there are no data currently reported on the role of hyperhomocysteinemia as a risk factor for cerebral venous thrombosis. High plasma levels of total homocysteine (tHcy) result from the connection between genetic and acquired determinants. Cerebral venous thrombosis is one of the commonest causes of stroke as far as Indian population is concerned. CVST usually predisposes in the state of pregnancy and puerperium. The pathological hallmark that is reported in CVST is haemorrhagic infarction. CVST predominantly occur in the young individuals and can present with a broad spectrum of clinical manifestations which include headache, altered sensorium, seizures, focal neurological deficits, papilloedema and cranial nerve palsies