Background: Cervical cancer worldwide is second only to breast cancer in incidence. The present study compared liquid-based cytology and conventional cytology for assessment of cervical pap smear. Materials & Methods: 84 females aged 18- 60 years presenting with complaints of abnormal vaginal discharge etc. were enrolled and specimen was collected for both conventional pap smear (group I) and liquid based cytology (group II) then colposcopic guided biopsy was performed.