Purpose: This study aimed to evaluate the effect of virtual reality and cold vibration application through the buzzy device on phlebotomy associated pain and physiological parameters (pulse rate and Spo2) among 5-10 years of children. Design Randomized: control trial Methods: Total 108 children were randomly assigned to three arms (Cold Vibration, Virtual reality and control) using blocked randomization method. Allocation concealment was ensured using Sequential Numbering Opaque Sealed Envelope. Pain scores were collected after phlebotomy from the children, researcher and the nurse using WBFS scale whereas pulse rate and Spo2 were recorded by a fingertip pulse oximeter. Result: During phlebotomy, thepain score and pulse rate were found to be lesser in virtual reality and cold vibration group as compared to the control group. There was a statistical difference in pain score between experimental and control group as perceivedamong the children (p < 0.000), Nurse (p < 0.000), and by the researcher (p < 0.000) during phlebotomy (Table 2). For pulse rate, a statically significant difference between experimental and control group was found (p < 0.05),whereas no statistically significant difference was found for SPO2 (p> 0.05). Conclusion: The current study proposed both virtual reality and cold vibration application were equally effective in alleviating the phlebotomy related pain and pulse rate of 5-10 years aged children. Hence the author advocates the use of these distraction methods in the clinical practice for pain management.