Introduction In India, chronic kidney disease (CKD) is presently the third most prevalent noncommunicabledisease. Kidney function is reduced progressively and irreversibly as a result of CKD. The most popular treatment for chronic renal disease is hemodialysis (HD). An arteriovenous fistula(AVF)is the most typical vascular access point for those who need to undergo hemodialysis. However, HD patients always have severe concerns about the pain that is associated with AVFcannulation. The researcher aims to assess the effectiveness of ice massage at the Hegu point on AVF puncture-related pain among hemodialysis. The main objective of the study is to evaluate the AVF puncture-related pain scores in HD patients with and without Hegu point icemassage and to correlate the AVF puncture-related pain scores with selected biographical variables.