Introduction: Anaemia is a condition in which haemoglobin (Hb) concentration and/or red blood cell (RBC) numbers are lower than normal and insufficient to meet an individual’s physiological needs of affects roughly one-third of the world’s population. Vitamin B-12, also called cobalamin, has the biggest and most intricate chemical structure of all the essential vitamins. Without vitamin B-12, cannot make enough heme to produce functional red blood cells. People with low vitamin B-12 levels develop vitamin B-12 deficiency anemia, which is characterized by blood cells poor in hemoglobin