Background: Labour is a natural physiological phenomenon of childbirth. Painless and short labor is desired by every woman and is a constant aim for obstetrician. To avoid prolonged labour and its ill effects, sedation, amniotomy, oxytocin and prostaglandin have been used. The aim of this study to compare the efficacy of drotaverine hydrochloride and valethamate bromide on cervical dilation in active labour at newly established tertiary care centre.